I was inspired to pick up a uke after seeing this and also made 'Something' the first thing I learned.
I always found it interesting that George was so fundamentally responsible for popularizing the sitar - one of the most difficult instruments to master - in the 60's, then advocated and popularized the uke - one of the easiest instruments to learn - in later life. I could almost imagine a certain degree of ironic humor intended with this on George's part, although it's probably not the case.
Fun to play, great at beach parties.